OXFORD, Miss. -- Jordan Ta'amu threw for three touchdowns and ran for two more as Mississippi scored on its opening five possessions Saturday to defeat Louisiana 50-22.
Ta'amu, in his third career start after replacing an injured Shea Patterson, finished 28 of 36 for 418 yards, opening with nine consecutive completions. Ta'amu added scoring runs of 1 and 8 yards as the Rebels (5-5, 2-4 SEC) raced to an insurmountable 35-7 lead early in the second quarter.
"It doesn't matter who you are playing. When your quarterback takes you for touchdowns on the first five possessions, that's pretty impressive," said interim Ole Miss coach Matt Luke. "We're fortunate here to have two really outstanding quarterbacks."
Louisiana (4-5, 3-2 Sun Belt) scored on a 31-yard run by Raymond Calais during the first half surge by the Rebels. Reserve quarterback Jordan Davis added fourth quarter scoring runs of 10 and 31 yards.
"We knew coming in that 22 points would not be enough," Louisiana coach Mark Hudspeth said. "They're outstanding, especially offensively. They've got a lot of weapons and we could not show them down enough in the first half."
A.J. Brown had 14 receptions for 185 yards, including touchdown catches of 31 and 27 yards. DaMarkus Lodge opened the early surge with a 37-yard touchdown reception. Jordan Wilkins and Eric Swinney added scoring runs of 8 and 10 yards, respectively.
"It's a lot of fun with these receivers and backs. I trust them" Ta'amu said. "A.J. is always going to do more than I expect when he has the ball. I've just got to make sure I get it to him."
The Rebels finished with 641 yards of total offense, 441 in the first half. Louisiana finished with no turnovers and 437 yards of total offense.
Louisiana: Defensive back Corey Turner had a game-high 13 tackles, including a sack and another tackle for loss. Louisiana played without four starters, running back Trey Ragas, guard Robert Hunt, linebackers Joe Dillon and Damar'ren Mitchell. The announcement of the suspensions was released 15 minutes before kickoff, but listed no other details.
Ole Miss: Wilkins had 14 carries for 124 yards that was overshadowed by Ta'amu and Brown. An SEC team, playing at home, is expected to defeat a Sunbelt Conference team and the Rebels settled the issue immediately.
With the victory, the resilient Rebels improved to .500, riding a two-game winning streak.
"We're 2-0 in November, with 12 days left," Luke said. "We have a lot to play for."
Ole Miss: The Rebels host Texas A&M Saturday in their home finale, before finishing on the road at archrival Mississippi State.